- What is frontotemporal dementia?
- Frontotemporal dementia, or FTD, refers to a group of neurological disorders caused by degeneration primarily involving the frontal and temporal regions of the brain. Depending on which networks are affected, it can cause prominent changes in behavior, personality, judgment, language or, in some forms, movement.
- What are the first signs of FTD?
- Early symptoms often involve behavior and personality—loss of inhibition, socially inappropriate behavior, loss of empathy, apathy, impulsivity, poor judgment, repetitive behaviors, or changes in eating habits. In language-predominant forms, early symptoms involve difficulty finding, producing or understanding words.
- How is FTD different from Alzheimer's disease?
- They are different neurodegenerative disorders. Memory loss is commonly an early feature of Alzheimer's disease, while FTD more often begins with changes in behavior, personality, executive function or language, and memory can sometimes remain relatively preserved early on. Symptoms overlap, so this distinction alone does not diagnose either condition.
- At what age does frontotemporal dementia usually begin?
- FTD tends to begin at a younger age than many other forms of dementia, and it is one of the more common causes of dementia in people under 65. Age alone, however, does not establish or exclude the diagnosis.
- Can FTD cause personality changes?
- Yes. Significant changes in personality, social behavior, empathy, motivation and judgment are characteristic of the behavioral form of FTD, and these changes are often noticed by family before the person notices them.
- Is frontotemporal dementia hereditary?
- Genetics play an important role in some cases. A significant proportion of people with FTD have a family history of FTD or a related neurological disorder, and some cases are caused by identifiable genetic variants. Genetic counseling or testing may be considered in selected patients, particularly with a strong family history or relatively young age of onset.
- How is FTD diagnosed?
- There is no single simple test that diagnoses every case. Evaluation may include a detailed history from the patient and family, a neurological examination, cognitive testing, assessment of behavior and language, blood testing to look for other causes, brain MRI or other imaging, and additional specialized testing when appropriate.
- Is there a treatment for frontotemporal dementia?
- There is currently no cure that stops or reverses the underlying neurodegeneration. Treatment focuses on managing symptoms, maintaining function and safety, supporting caregivers, and addressing behavioral, language, movement and other problems as they arise.