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How Do You Treat Neuropathy?

Treating peripheral neuropathy involves two important goals: identifying and treating the underlying cause of the nerve damage, and treating the symptoms the neuropathy causes. Treatment therefore depends on why someone has neuropathy.

Written and medically reviewed by Amarish Dave, DO, board-certified neurologist. This page is educational and does not replace an individual medical evaluation.

Video with Amarish Dave, DO, Board-Certified Neurologist

Potential causes of neuropathy include diabetes, vitamin deficiencies, certain medications or chemotherapy, alcohol or toxins, autoimmune disorders, infections, inherited conditions and other medical problems. Because the causes differ, the treatment plan differs from one patient to the next.

Treating the cause of neuropathy

Identifying the cause matters because some causes can be treated or controlled. Examples include improving diabetes control, correcting an appropriate vitamin deficiency, addressing medication or toxin exposure when possible, or specifically treating an inflammatory or autoimmune neuropathy.

Some neuropathies may improve when the underlying cause is corrected, although recovery depends on the cause and the degree of nerve damage.

How is nerve pain treated?

Medications do not necessarily repair the damaged nerve, but they can reduce burning, tingling, electrical or painful sensations. Depending on the individual patient, treatments for neuropathic pain may include:

  • Gabapentin
  • Pregabalin
  • Duloxetine
  • Certain tricyclic antidepressants
  • Topical treatments such as lidocaine or capsaicin

Medication choice depends on the patient’s symptoms, other medical conditions, current medications and potential side effects.

Exercise, balance and foot care

Treatment isn’t only medication. Physical therapy and appropriate exercise may help people experiencing weakness, walking difficulty or balance problems. People with decreased sensation in their feet should also pay particular attention to foot care, because an injury may go unnoticed.

Why finding the cause matters

“Neuropathy” describes nerve damage but does not identify its cause. A neurological evaluation for neuropathy may include a detailed history and neurological examination, blood testing and, when appropriate, nerve conduction studies and EMG. Additional testing may be needed depending on the suspected type of neuropathy.

New or worsening symptoms deserve evaluation

New, rapidly progressive or unexplained numbness, weakness or other neurological symptoms should be medically evaluated rather than assumed to be a benign neuropathy.

Key takeaways

  • Neuropathy treatment has two goals: treat the underlying cause, and treat the symptoms.
  • Causes include diabetes, vitamin deficiencies, medications or chemotherapy, alcohol or toxins, autoimmune disorders, infections and inherited conditions.
  • Some neuropathies improve when the cause is corrected; recovery depends on the cause and degree of nerve damage.
  • Nerve pain can be treated with medications such as gabapentin, pregabalin, duloxetine, certain tricyclic antidepressants, or topical treatments.
  • Exercise, physical therapy, balance training and foot care are important parts of treatment.
  • EMG and nerve conduction studies may help clarify the type and severity of nerve damage.

Continue learning about neuropathy and nerve care

Frequently asked questions

Can neuropathy be cured?
It depends on the cause. Some neuropathies—such as those caused by a vitamin deficiency or a medication effect—can improve substantially when the cause is corrected. In other cases, the goal is to stabilize the neuropathy, control symptoms and prevent complications such as falls and foot injuries.
Can damaged nerves heal?
Peripheral nerves can regenerate, but the process is slow—often measured in months—and recovery depends on the cause and the degree of nerve damage. Treating the underlying cause gives nerves the best chance to recover.
What medications are used for neuropathy pain?
Depending on the individual patient, medications used for neuropathic pain include gabapentin, pregabalin, duloxetine, certain tricyclic antidepressants, and topical treatments such as lidocaine or capsaicin. The choice depends on symptoms, other medical conditions, current medications and potential side effects.
Does exercise help neuropathy?
Yes. Appropriate exercise and physical therapy can help with weakness, walking difficulty and balance problems, and activity also supports metabolic health—which matters in the most common forms of neuropathy. People with reduced foot sensation should combine exercise with careful foot care.
What causes neuropathy?
Potential causes include diabetes and prediabetes, vitamin deficiencies, certain medications or chemotherapy, alcohol or toxins, autoimmune and inflammatory disorders, infections, inherited conditions, and other medical problems. Sometimes no cause is identified.
When should I see a neurologist for numbness or tingling?
Consider an evaluation when numbness, tingling or burning persists, spreads, affects both feet or both hands, is accompanied by weakness or balance problems, or interferes with sleep and walking. New, rapidly progressive or unexplained symptoms should be evaluated promptly.

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Have numbness, tingling, burning or other symptoms that could be neuropathy?

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